Signal Transduction Reagents and Kits
Aat Bioquest Calbryte™ 520 AM | 1mg
Calbryte™ 520, AM is a novel fluorescent and cell-permeable indicator for the measurement of intracellular calcium. Like other dye AM esters, Calbryte™ 520 AM is non-fluorescent and non-activatable. Once Calbryte™ 520 AM enters the cell, it is readily hydrolyzed by intracellular esterase where it becomes activated and responsive to calcium. The activated indicator is now a polar molecule that is incapable of freely diffusing through the cell membrane, essentially trapping it inside the cell. Upon binding calcium ions, Calbryte™ 520 produces a bright fluorescence signal with extremely high signal/background ratio. It has the identical excitation and emission wavelength as Fluo-4, thus the same Fluo-4 assay settings can be readily applied to Calbryte™ 520-based calcium assays.
Echelon Biosciences Research Labs Chymotrypsin like enzyme substrate - 5 mg,
Chymotrypsin like enzyme substrate - 5mg , Succinyl-Leu-Leu-Val-Tyr-AFC Category/Application: Enzyme Substrates This item is non returnable
Cell Signaling Technology SignalSlide Phospho-Met (Tyr1234/1235) IHC Controls 1 Pack
SignalSlide Phospho-Met (Tyr1234/1235) IHC Controls 1 Pack
Revvity Health Sciences Inc HTRF cAMP Gs HiRange Detection Kit Standard, 10 Vials
HTRF cAMP Gs HiRange Detection Kit Standard, 10 Vials
Echelon Biosciences Research Labs XY-17 (LPA3 Agonist) 0.5 mg
XY-17 is a fluorinated phosphonate analog of lysophosphatidic acid (LPA). XY-17 is not hydrolyzed by lipid phosphate phosphatase (LPP) and acts as an agonist of the LPA3 receptor. This item is non returnable
Echelon Biosciences Research Labs SHUTTLE PIP KIT PI(5)P
Echelon Biosciences - Shuttle PIP Kit - P-9005 - PI(5)P This item is non returnable
Echelon Biosciences Research Labs PI(3)P DIC8 AMMONIUM SALT 1 mg
PI(3)P diC8 (Phosphatidylinositol 3-phosphate diC8) is a synthetic, purified dioctanoyl PI(3)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4. This item is non returnable
Medchemexpress LLC Veratridine | 71-62-5 | 10 MG
Veratridine is a plant neurotoxin and a voltage-gated sodium channel (VGSCs) agonist. It inhibits the peak current of Nav1.7 with an IC50 of 18.39 μM. It regulates sodium ion channels by activating them, preventing channel inactivation, and increasing sodium ion flow. This product is for research use only.
- Plant neurotoxin
- Voltage-gated sodium channels (VGSCs) agonist
- Inhibits peak current of Nav1.7
- Regulates sodium ion channels by activation
- Prevents channel inactivation
- Increases sodium ion flow
Enzo Life Sciences Z-prolyl-prolinal (25mg). CAS: 86925-97-5
A potent and selective inhibitor of prolyl endopeptidase (PEP/PREP/POP, EC 3.4.21.26). Ki=0.35 nM for mouse brain enzyme. Inhibits the cleavage of arginine-vasopressin, gonadotropin-releasing hormone, and other peptides. Alternative name: Z-PP-CHO. Purity: ≥97% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Folic acid (10g). CAS: 59-30-3
Alternative name: Pteroylglutamic acid. Purity: ≥97% (HPLC). Solubility: Soluble in diluted acids or alkaline solutions; slightly soluble in water or methanol; almost insoluble in organic solvents. Long Term Storage: +4°C.
Echelon Biosciences Research Labs BODIPY FL PI(3)P 100 ug
BODIPY FL PI(3)P (BODIPY FL Phosphatidylinositol 3-phosphate) is a water soluble analog of PI(3)P labeled with the green fluorophore, Bodipy-FL at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4. This item is non returnable
Medchemexpress LLC Malic enzyme inhibitor ME1 | 522649-59-8 | 99.7% | 351.40 g·mol⁻¹ | C20H21N3O3 | 50MG
Malic enzyme inhibitor ME1 is a small-molecule, selective inhibitor of cytosolic malic enzyme (ME1) used for biochemical and cellular research. It exhibits potent inhibition of ME1 (IC50 = 0.15 μM) and is supplied as a white to off-white solid with high purity and defined storage recommendations.
- Potent ME1 inhibition (IC50 = 0.15 μM).
- High purity suitable for biochemical assays (99.7%).
- Supplied as a solid, white to off-white.
- Highly soluble in DMSO; may require sonication and warming.
- Stable when stored under recommended conditions in powder or solution.
Revvity Health Sciences Inc HTRF Human IL-17A / IL17RA Binding Kit Standard
HTRF Human IL-17A / IL17RA Binding Kit Standard
Echelon Biosciences Research Labs 3S-PTDINS(3,4,5)P3 DIC16 500 ug
PtdIns(3,4,5)P3 3-phosphothioate, diC16 (3S-PtdIns(3,4,5)P3, diC16) is a water-soluble, synthetic PI(3,4,5)P3 analog in which the 3-phosphate has been rendered metabolically stable as a phosphorothioate. P-3S908 shows 90% inhibition of PTEN at 0.4M. This item is non returnable